BluRay 45GB Double Layer burning

I have about 10 original "small" BluRay 25Gb which I ripped to my NAS. I also have about 10 which are about 38-48 Gb "big" BluRay discs they are also ripped as ISO file to the NAS. When I go on holidays I used to burn a copy of a DVD or "small" BluRay so that i didn't have to take the original copy with me. This worked satisfactory Now I tried to burn Double Layer BluRay discs form a couple of those working ISO files. NERO 2014 correctly burns them. But the copy can't be read on my PC nor on my BluRay players. What can be wrong?
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